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Hydroxyethyl Starch 130/0.4 Sodium Chloride Injection (Qiangyijidianfen130/0.4 Lühuana Zhusheye)

Please peruse the instructions carefully before using and following the advice of a physician. 

 

[Drug Name]

Common Name: Hydroxyethyl Starch 130/0.4 Sodium Chloride Injection

English Name: Hydroxyethyl Starch 130/0.4 Sodium Chloride Injection

Chinese Pinyin: Qiangyijidianfen130/0.4 Lühuana Zhusheye

 

[Characters]

This drug is a colorless transparent liquid with slight viscosity and a little opalescence and salty taste. 

[Indications]

It is used to cure and prevent hypovolemia and acute normovolaemic haemodilution (ANH).

 

[Specification]

500ml: 30g of Hydroxyethyl Starch 130/0.4 and 4.5g of sodium chloride injection.

 

[Usage and Dosage]

It is used for vein injection.

The first 10-20ml should be injected slowly and patient should be observed closely (to prevent possible allergic reaction). Daily dosage and injection speed should be based on patient’s blood loss, maintenance and recovery of blood hemodynamic parameters and dilution effect. 

When a patient without risk of angiocarpy or lung takes colloid expander, his or her hematokrit should not be lower than 30%. Daily maximum dosage should be 33ml/kg based on weight. 

Based on patient’s needs, this drug can be used continuously in several days. Duration of treatment depends on maintenance duration and degree of hypovolemia and blood hemodynamic parameters and dilution effect. 

For long-period treatment with daily maximum dosage, limited experience is available currently. Patients should follow the medical advice when taking this drug.

 

[Adverse Reaction]

Rare patients may have allergic reaction (allergic reaction, similar to symptoms of moderate flu, like bradycardia, tachycardia, bronchospasm, non-cardiac emphysema) when taking drugs containing Hydroxyethyl Starch. During infusion, if a patient suffers from intolerant reaction, infusion should be stopped immediately and proper cure treatment should be given. When taking Hydroxyethyl Starch, patient’s hemodiastase concentration will increase. At this time, the diagnosis of pancreatitis can be influenced. Long-period application of large dosage of Hydroxyethyl Starch will cause skin pruritus. Dilution effect may result in dilution of blood ingredients such as coagulation factor and plasma protein and decrease of hematokrit. Abnormal coagulation of blood may occur in relation to dosage when Hydroxyethyl Starch is taken. 

 

[Contraindication]

-Overload of liquid (excessive water), including pneumonedema

- Kidney failure with little or no urine

- Patients receiving dialysis treatment 

- Intracranial hemorrhage

- Serious hypernatremia or hyperchloremia

- Allergic to Hydroxyethyl Starch and/or other ingredients in this drug